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The four stages of rheumatoid arthritis are known as synovitis, pannus, fibrous ankylosis, and bony ankylosis - Stage I: Synovitis. During stage I, you may start having mild symptoms, including joint pain and joint stiffness. Stage II: Pannus. Stage III: Fibrous Ankylosis. Stage IV: Bony Ankylosis.

The exact cause of rheumatoid arthritis is unknown. It is thought to be due to a combination of genetic, environmental and hormonal factors.

As RA progresses, the inflamed synovium invades and destroys the cartilage and bone within the joint. The surrounding muscles, ligaments and tendons that support and stabilize the joint become weak and unable to work normally. These effects lead to the pain and joint damage often seen in rheumatoid arthritis. Researchers studying rheumatoid arthrit

Scientists throughout the world are studying many promising areas of new treatment approaches for rheumatoid arthritis. Indeed, treatment guidelines are evolving with the availability of newer treatments. These areas include treatments that block the action of the special inflammation factors, such as tumor necrosis factor TNF alpha, B-cell and T-c

Tender, warm, swollen joints; symmetrical pattern of affected joints; and joint inflammation often affecting the wrist and finger joints closest to the hand and sometimes other joints such as the neck, shoulders, elbows, hips, knees, ankles and feet. Other symptoms are fatigue, occasional fevers, a loss of energy and pain and stiffness lasting for